Search on: ANTIGENS, CD274 
Descriptors Found: 1
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Descriptor English:   Antigens, CD274 
Descriptor Spanish:   Antígenos CD274 
Descriptor Portuguese:   Antígenos CD274 
Synonyms English:   Programmed Cell Death 1 Ligand 1 Protein  
Tree Number:   D12.776.467.150.300
D12.776.543.095.300
D23.050.301.264.035.276.300
D23.050.301.285.400
D23.101.100.110.276.300
D23.529.168.300
Definition English:   An inhibitory B7 antigen that has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN. CD274 antigen provides negative signals that control and inhibit T-cell responses and is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION. 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54623 
Unique Identifier:   D060890 

Occurrence in VHL:
 

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